How Clinical AI Fails: A Field Guide

How Clinical AI Fails: A Field Guide

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Eight failures to look for, with an example and a way to catch each

1. Made-up facts

What it looks like: The summary mentions a test or diagnosis that isn’t in the chart.

How to catch it: Check every claim against its source passage.

2. Stale or wrong source 

What it looks like: The answer follows a withdrawn policy, or a national guideline that contradicts your protocol.

How to catch it: Test with draft, withdrawn and outdated documents loaded on purpose.

3. Missed negation or certainty

What it looks like: “Ruled out pneumonia” is read as “has pneumonia,” or “suspected” becomes “confirmed.”

How to catch it: Test pairs of near-identical statements with opposite meanings.

4. Copied-forward facts

What it looks like: An old medication keeps appearing because every note repeats it.

How to catch it: Compare AI answers with structured data such as the medication list.

5. Citation that doesn’t support the claim

What it looks like: The answer links to a real document, but the passage says something else.

How to catch it: Audit a sample of citations each month, reading the passage itself.

6. Wrong “I don’t know”

What it looks like: It declines when the answer is in the chart, or answers confidently when it isn’t.

How to catch it: Track both kinds of mistakes, not just overall accuracy.

7. Wrong patient or restricted data

What it looks like: Information from another encounter, a duplicate record, or a chart the user shouldn’t see.

How to catch it: Test with restricted users and duplicate or merged records.

8. Missing documentation treated as “no”

What it looks like: “Not documented” is read as “doesn’t have it,” so a summary says there is no history of a condition.

How to catch it: Ask questions where the chart is silent and check the wording of the answer.

Pro Tip: When an answer is wrong, find out which step failed (the source, the search or the answer) before blaming the model.